Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 13 de 13
Filter
1.
Braz. oral res. (Online) ; 35: e067, 2021. tab, graf
Article in English | LILACS, BBO | ID: biblio-1278592

ABSTRACT

Abstract Dental caries remains a major public health problem, with a higher prevalence among in adolescence. The present study aimed to assess the dental caries spectrum profile in children and adolescents in Brazilian public schools. A cross-sectional study was performed in two public schools in Brazil to examine the permanent teeth of children and adolescents. The dental caries were assessed by applying the Caries Assessment Spectrum and Treatment (CAST) instrument, and the results were distributed as per disease status (healthy/codes 0-2; pre-morbidity/code 3; morbidity/code 4-5; severe morbidity/codes 6-7; mortality/code 8) and by severity as per the CAST-F1 formula (no severity, mild, moderate, and severe). The CAST data were described by age groups (8-9 y, 10-11 y, 12-13 y, 14-15 y, 16-17 y, and 18-19 y). The Kruskal-Wallis test was used to investigate differences in CAST prevalence and severity among the groups (p < 0.05). Total 598 students were enrolled. Most of the subjects were male (53.34%) and belonged to the age group of 12-13 y (34.95%). The variables CAST 0/1 (p = 0.024), CAST (p = 0.024), and CAST-F1 (p = 0.029) showed significant differences among age groups, and the post hoc test showed the differences in these variables as per the age groups of 14-15 y and 16-17 y (CAST 0/1, p = 0.047; CAST, p = 0.047; CAST-F1, p = 0.033). The dental caries spectrum increased from 8 to 19 y with a peak in the prevalence and severity in the middle of adolescence.


Subject(s)
Humans , Male , Female , Child , Adolescent , Dental Caries/epidemiology , Schools , Brazil/epidemiology , DMF Index , Prevalence , Cross-Sectional Studies
2.
J. appl. oral sci ; 29: e20200609, 2021. tab, graf
Article in English | LILACS | ID: biblio-1154615

ABSTRACT

Abstract Objective To compare the effectiveness of ART restorations using High Viscosity Glass-ionomer cement (HVGIC) with conventional restorations using resin composite in Class II cavities of permanent teeth, in a 2-year follow-up. Methodology Seventy-seven restorations were made with each restorative material, Equia Fil-GC Corporation (ART restorations) and Z350-3M (conventional restoration), in 54 participants in this parallel and randomized clinical trial. Restorations were evaluated at 6 months, 1 and 2 years using the ART and the modified United States Public Health Service (USPHS) criteria. Chi-square test and Survival Analysis (p<0.05) were used for statistical analysis. Results The success rates for ART restorations were 98.7% (6 months) and 95.8% (1 year) for both criteria. At 2 years, success rate was 92% and 90.3% when scored by the modified USPHS and ART criteria (p=0.466), respectively. The success rates for conventional restorations were 100% (6 months), 98.7% (1 year) and 91.5% (2 years) for both assessment criteria. ART restorations presented a lower survival rate by the criterion of ART (83.7%) when compared to the modified USPHS criterion of (87.8%), after 2 years (p=0.051). The survival of conventional restorations was 90.7% for both evaluation criteria. Conclusion At the 2-years follow-up evaluation, no statistically significant difference was observed between the success rate of ART restorations with HVGIC compared to conventional restorations with resin composite in Class II cavities of permanent teeth.


Subject(s)
Humans , Dental Caries , Glass Ionomer Cements , Viscosity , Prospective Studies , Follow-Up Studies , Composite Resins , Dental Restoration, Permanent
3.
Braz. oral res. (Online) ; 34: e053, 2020. tab, graf
Article in English | LILACS, BBO | ID: biblio-1132666

ABSTRACT

Abstract The objective was to evaluate the compressive strength (CS), diametral tensile strength (DTS), flexural strength (FS), and Knoop microhardness (KH) of different conventional restorative glass-ionomer cements (GICs) and to correlate these mechanical properties (MP) with the stabilization time (ST) of their chemical bonds. Eighteen GICs were tested: Bioglass [B], Chemfil Rock [CR], Equia Forte [EF], Gold Label 2 [GL2], Gold Label 9 [GL9], Glass Ionomer Cement II [GI], Ionglass [IG], Ion Z[ IZ], Ionomaster [IM], Ionofil Plus [IP], Ionostar Plus [IS], Ketac Molar Easymix [KM], Magic Glass [MG], Maxxion R [Ma], Riva Self Cure [R], Vidrion R [V], Vitro Fil [VF] and Vitro Molar [VM]. The mechanical strength tests were performed in a universal testing machine. KH readings were done with a diamond indenter. STs were examined by Fourier Transform Infrared spectroscopy (FTIR). Data were analyzed with ANOVA and Tukey test (p<0.05). The Spearman rank test was used to evaluate the dependence between the MPs and ST results. The highest MP values were EF, GL2, GL9, GI and KM and the lowest for MG, MA, B, VF and IM. The longest ST was for GL2 and the shortest was for B. ST correlated positively with MP. GICs with longer chemical bonds ST are generally stronger and the ST value obtained from FTIR was useful in predicting the strength of GICs tested.


Subject(s)
Self-Curing of Dental Resins/methods , Glass Ionomer Cements/chemistry , Reference Values , Tensile Strength , Time Factors , Materials Testing , Reproducibility of Results , Analysis of Variance , Spectroscopy, Fourier Transform Infrared , Compressive Strength , Flexural Strength , Hardness Tests
4.
J. appl. oral sci ; 27: e2018357, 2019. tab, graf
Article in English | LILACS, BBO | ID: biblio-984572

ABSTRACT

Abstract Objectives To perform a systematic review of test methodologies on conventional restorative glass-ionomer cement (GIC) materials for mechanical and optical properties to compare the results between different GICs. Material and Methods Screening of titles and abstracts, data extraction, and quality assessments of full-texts were conducted in search for in vitro studies on conventional GICs that follow the relevant specifications of ISO standards regarding the following mechanical and optical properties: compressive strength, flexural strength, color, opacity and radiopacity. Sources The Latin American and Caribbean Health Sciences (LILACS), Brazilian Bibliography of Dentistry (BBO) databases from Latin-American and Caribbean System on Health Sciences Information (BIREME) and PubMed/Medline (US National Library of Medicine - National Institutes of Health) databases were searched regardless of language. Altogether, 1146 in vitro studies were selected. Two reviewers independently selected and assessed the articles according to pre-established inclusion/exclusion criteria. Among all the properties investigated, only one study was classified as being of fair quality that tested compressive strength and was included. It was observed that many authors had not strictly followed ISO recommendations and that, for some properties (diametral tensile strength and microhardness), there are no guidelines provided. Conclusions It was not possible to compare the results for the mechanical and optical properties of conventional restorative GICs due to the lack of standardization of studies.


Subject(s)
Glass Ionomer Cements/chemistry , Materials Testing , Color , Compressive Strength , Flexural Strength , Glass Ionomer Cements/standards
5.
Braz. dent. sci ; 22(1): 111-117, 2019. tab, ilus
Article in English | LILACS, BBO | ID: biblio-986946

ABSTRACT

Objective: To evaluate the fracture resistance (RF) of Class II Glass-ionomer Cement (GIC) ART restorations with and without proximal retentions. Material and Methods: 20 freshly extracted human molars were used. Forty (40) standard Mesial-Occlusal (MO) and DistalOcclusal (DO) preparations (20 for each material) were performed with a 245 bur. The unprepared surfaces of the teeth were protected with nail polish and the specimens submerged in 0.5Mol EDTA solution, pH 7.4 for 8h under stirring. The preparations were finished with dentine spoons and 50% received proximal retention with # 3 excavators. 20 cavities were restored with Chemfil Rock (10 with retention and 10 without retention) and 20 cavities were restored with Equia Fil (10 with retention and 10 with no retention) and were stored in an oven at 37ºC and 100% relative humidity for 24h and submitted to axial compression loading in Test Machine - EMIC at a rate of 0.5 mm / minute, until restoration fracture occurred. The values were analyzed by two-way ANOVA (p<0.05). Results: ChemFil Rock presented 300.84 (69.20) (without retention) and 361.70 (81.08) (with retention) and Equia Fil showed 314.60 (69.97) (without retention) and 366.67 (103.38) (with retention). Data obtained with retention were statistically superior to those obtained with non-retained ART restorations (p=0.014). No statistical differences were detected between materials (p=0.761). Conclusion: Retentive grooves improved fracture resistance of Class II GIC ART restorations. (AU)


Objetivo: avaliar a resistência à fratura (FR) de restaurações de ART de Classe II de Cimento de ionômero de vidro (CIV) com e sem retenções proximais. Material e Métodos: Foram utilizados 20 molares humanos recém-extraídos. 40 cavidades padronizadas no sentido Mesial-Oclusal (MO) e Oclusal-Distal (OD) (20 para cada material) foram realizadas com uma broca 245. Os preparos cavitários foram submersos em solução 0,5 mol Mol EDTA, pH 7,4 por 8h sob agitação e foram finalizados com colheres de dentina, nos quais 50% receberam retenções proximais com escavadores #3. 20 cavidades foram restauradas com Chemfil Rock (10 com e 10 sem retenção) e 20 cavidades foram restauradas com Equia Fil (10 com e 10 sem retenção) e armazenadas em estufa a 37ºC e 100% de umidade relativa por 24h e submetidos a carga axial de compressão na máquina de ensaios EMIC a uma taxa de 0,5mm/min, até que a fratura de restauração ocorresse. Os valores foram analisados por ANOVA twoway (p<0,05). Resultados: ChemFil Rock apresentou 300.84 (69.20) (sem retenção) e 361.70 (81.08) (com retenção) e o Equia Fil apresentou 314.60 (69.97) (sem retenção) e 366.67 (103.38) (com retenção). Os dados obtidos com retenção foram estatisticamente superiores àqueles sem retenção (p=0.014). Não houve diferença estatística entre os materiais (p=0.761). Conclusão: Os sulcos retentivos melhoraram a resistência à fratura de restaurações de ART de Classe II de Cimento de ionômero de vidro (CIV).(AU)


Subject(s)
Weight-Bearing , Dental Materials , Glass Ionomer Cements
6.
Braz. dent. sci ; 21(1): 126-132, 2018. ilus
Article in English | LILACS, BBO | ID: biblio-881971

ABSTRACT

Biological restorations, involving a technique of uniting autogenous or homogenous dental fragment for use as the primary restorative material, are an alternative for morphological and functional reestablishment of teeth with extensive coronal destruction. Despite the wide range of restorative materials available in dentistry, no material has proved to be as efficient as the natural tooth structure. This article illustrates a therapeutic option for rehabilitating a devitalized mandibular tooth with a weakened coronal remainder by using the biological restoration technique. The authors present the sequence of planning and performing the technique, such as the characteristics of preparation of the tooth and fragment, impression taking, cutting and cementation of the fragment, and the four-year follow-up of the biological restoration, which shows the success of the technique with marginal adaptation and satisfactory esthetic appearance. (AU)


As restaurações biológicas, envolvendo uma técnica de união de fragmentos dentários autógenos ou homogêneos como principal material restaurador, são uma alternativa para o restabelecimento morfológico e funcional de dentes com destruição coronal extensa. Apesar da ampla gama de materiais restauradores disponíveis na odontologia, nenhum material provou ser tão eficiente quanto a estrutura dentária natural. Este artigo ilustra uma opção terapêutica para reabilitar um molar inferior desvitalizado com um remanescente coronal fragilizado, utilizando a técnica de restauração biológica. Os autores apresentam a sequência de planejamento e execução da técnica, tais como as características de preparação do dente e do fragmento, moldagem, recorte e cimentação do fragmento, e o acompanhamento clínico de 3 anos da restauração biológica, mostrando o sucesso da técnica com uma adaptação marginal e aparência estética satisfatória (AU)


Subject(s)
Dental Cements , Dental Restoration, Permanent , Tooth, Nonvital
7.
ROBRAC ; 26(79): 9-15, out./dez. 2017. tab
Article in English | LILACS | ID: biblio-906015

ABSTRACT

Purpose: The aim of the present case-control study was to investigate whether there was any association between occupation and oral squamous cell carcinoma (OSCC) in a Brazilian population. Methods: This population-based study investigated an occupation that was classified according to the International Standard Classification of Occupations. The sample consisted of 665 individuals, of whom 133 were cases of OSCC, selected from reference hospitals for cancer in Paraíba; and 532 were part of a control group, paired by age, gender, place and smoking habit, who participated in the study. Results: There was statistically significant association between OSCC and occupation (p<0.001), alcohol consumption (p<0.001) and marital status (p=0.003). The variables marital status, occupation, alcoholism and smoking were shown to be statistically associated with the development of cancer of the oropharynx with Odds Ratio (OR) ranging from 1.8 to 11.2 Conclusion: Occupational exposure to chemical and physical carcinogenic substances, as well as the condition of living with a partner may be raised as possible risk factors for the development of cancer of the mouth and oropharynx.


Objetivo: O presente estudo de caso-controle teve como objetivo investigar se existe associação entre ocupação e carcinoma de células escamosas orais (OSCC) em uma população brasileira. Métodos: Este estudo populacional investigou a ocupação que foi classificada de acordo com a Norma Internacional de Classificação de Ocupações. Foram incluídos 665 indivíduos, sendo 133 casos de OSCC, selecionados de hospitais de referência para câncer na Paraíba e 532 participantes do grupo controle, pareados por idade, sexo, local e tabagismo. Resultados: Houve associação estatisticamente significativa entre ocupação (p<0,001), consumo de álcool (p<0,001) e estado civil (p=0,003). As variáveis estado civil, ocupação, alcoolismo e tabagismo mostraram-se estatisticamente associadas ao desenvolvimento de câncer da orofaringe com Odds Ratio (OR) entre 1,8 e 11,2. Conclusão: A exposição ocupacional às substâncias químicas e físicas cancerígenas, bem como a condição de viver com um parceiro podem aumentar a possibilidade de fatores de risco para o desenvolvimento de câncer de boca e orofaringe.

8.
Braz. dent. j ; 28(2): 172-178, mar.-Apr. 2017. tab, graf
Article in Portuguese | LILACS | ID: biblio-839144

ABSTRACT

Resumo Os novos materiais restauradores em desenvolvimento devem evitar danos aos tecidos dentários. Portanto, o objetivo deste estudo foi avaliar a biocompatibilidade de uma marca comercial de cimento de ionômero de vidro convencional (CIV) modificado com microfibras de celulose (CIV+MC) ou nanocristais de celulose (CIV+NC) através da implantação de três amostras em tecido subcutâneo na região dorsal de 15 ratos Rattus norvegicus albinus. Cada rato recebeu um exemplar de cada cimento, resultando nos seguintes grupos (n=15): Grupo CIV (controle, n=15), Grupo CIV+MC e Grupo CIV+NC. Nos intervalos de 7, 30 e 60 dias os animais foram sacrificados e os seguintes aspectos foram avaliados histologicamente: tipo de células inflamatórias, fibroblastos, vasos sanguíneos, macrófagos, células gigantes, tipo de reação inflamatória e espessura da cápsula (µm). Estes eventos foram quantitativamente classificados conforme os escores: (-) ausente, (+) suave, (++) moderado e (+++) intenso. Os resultados foram analisados estatisticamente pelo teste Kruskal-Wallis e pós-teste Mann-Whitney. Aos 7 dias, o Grupo CIV+NC demonstrou um nível mais elevado de reparação tecidual porque havia maior quantidade de fibroblastos (p=0,022) e uma menor quantidade de macrófagos (p=0,008) e células mononucleares (p=0,033). Neutrófilos e células gigantes estavam ausentes em todos os períodos experimentais. Aos 60 dias, o Grupo CIV+NC apresentou cápsula de tecido fibroso com espessura mais reduzida (26,72±2,87 µm) em comparação ao Grupo CIV+MC (41,21±3,98 µm (p=0,025). No geral, todos os materiais apresentaram satisfatória biocompatibilidade, no entanto, o cimento de ionômero de vidro modificado com nanocristais de celulose proveu reparação tecidual mais avançada comparativamente aos demais materiais avaliados.


Developing new restorative materials should avoid damage to tissue structures. This study evaluated the biocompatibility of a commercial dental glass ionomer cement (GIC) mechanically reinforced with cellulose microfibers (GIC+CM) or cellulose nanocrystals (GIC+CN) by implantation of three test specimens in subcutaneous tissue in the dorsal region of 15 Rattus norvegicus albinus rats. Each rat received one specimen of each cement, resulting in the following groups (n=15): Group GIC (Control), Group GIC+CM and Group GIC+NC. After time intervals of 7, 30 and 60 days, the animals were sacrificed and the following aspects were histologically evaluated: type of inflammatory cells, fibroblasts, blood vessels, macrophages, giant cells, type of inflammatory reaction and capsule thickness (µm). These events were scored as (-) absent, (+) light, (++) moderate and (+++) intense. The results were statistically analyzed by Kruskal-Wallis test and Mann-Whitney post test. At 7 days, Group GIC+NC showed more favorable tissue repair because quantitatively there were more fibroblasts (p=0.022), fewer macrophages (p=0.008) and mononuclear cells (p=0.033). Polymorphonuclear neutrophils and giant cells were absent in all experimental periods. At 60 days, test specimens in Group GIC+NC were surrounded by a fibrous tissue capsule with reduced thickness (26.72±2.87 µm) in comparison with Group GIC+CM (41.21±3.98 µm) (p=0.025). In general, all biomaterials showed satisfactory biocompatibility, but glass ionomer cement modified with cellulose nanocrystals showed a more advanced tissue repair.


Subject(s)
Animals , Rats , Biocompatible Materials , Cellulose/chemistry , Nanoparticles/chemistry , Glass Ionomer Cements/chemistry
9.
Pesqui. bras. odontopediatria clín. integr ; 17(1): e3732, 13/01/2017. tab
Article in English | LILACS, BBO | ID: biblio-914466

ABSTRACT

Objective: To investigate if an association exists between diet and oral squamous cell carcinoma (OSCC) in a Brazilian population. Material and Methods: This populationbased study investigated food groups intaken by means of a quantitative food frequency questionnaire (QFFQ) validated for use in Brazil. It was included 665 individuals, being 133 cases of OSCC, selected from reference hospitals for cancer in Paraíba and 532 being part of a control group, paired by age, gender, place and smoking habit took part in the study. Food consumption related to cases and control groups were evaluated by QFFQ. The Chi-square test was carried out in order to verify if there was association between the categorical variables. The level of significance was 5%. Conditional logistic regression was performed by the Enter method in order to verify the odds ratio of independent variables that predict OSCC. Results: It was found statistical association between OSCC and: processed and variety meats (p=0.048), dairy products (p<0.001), oils and fats (p<0.001) and alcoholic beverages (p<0.001). The high consumption of cereals and tubers (OR=0.53; CI95%: 0.29-0.96; p=0.0039) acted as protection factor for OSCC. Conclusion: Data of the present research suggest that the ingestion of animal fat, food rich in salt and refined carbohydrates were associated with OSCC cases.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Carcinoma, Squamous Cell/pathology , Case-Control Studies , Diet/methods , Mouth Diseases/pathology , Brazil , Chi-Square Distribution , Eating , Logistic Models , Surveys and Questionnaires
10.
Sci. med. (Porto Alegre, Online) ; 26(1): 21980, jan-mar 2016.
Article in Portuguese | LILACS | ID: biblio-836857

ABSTRACT

Objetivos: Investigar as correlações existentes entre saúde bucal, ansiedade, depressão, estresse, alterações cognitivas e uso de medicamentos em idosos. Métodos: Os dados foram coletados em domicílio, por meio de questionários sobre dados sociodemográficos e uso de medicações; exames bucais para investigar o índice de dentes cariados, perdidos e obturados; e instrumentos para avaliar a presença de distúrbios psicossociais. Os seguintes instrumentos foram aplicados: Mini Exame do Estado Mental (alterações cognitivas), Escala de Katz (grau de dependência), Inventário de Depressão de Beck, Escala de Depressão Geriátrica (depressão), Inventário de Ansiedade de Beck (ansiedade) e Inventário de Sintomas de Stress para adultos de Lipp (estresse). Também se investigou a quantidade de remédios usados. Foi realizada análise descritiva e teste de correlação de Spearman. Resultados: Foram incluídos 37 idosos com idade média de 73,41 anos. O índice CPO-D médio foi 25,38. Dos 37 idosos, 21,6% foram classificados com depressão leve/moderada, 45,9% apresentavam ansiedade, 78,4% tinham comprometimento cognitivo e 54,1% tinham polifarmácia menor. Foram encontradas correlações estatisticamente significativas de forma positiva e moderada entre idade e saúde bucal; de forma negativa moderada entre idade e alterações cognitivas; e de forma positiva forte entre depressão e estresse resistência e entre ansiedade e estresse resistência. Conclusões: Saúde bucal, ansiedade, depressão, estresse e medicação foram fatores correlacionados na amostra de idosos estudada.


Aims: To investigate the correlation between oral health, anxiety, depression, stress, cognitive impairment, and use of medications in the elderly. Methods: Data were collected using household survey questionnaires on sociodemographic variables and use of medications; oral examinations for detection of decayed, missing, and filled teeth; and questionnaires to verify the presence of psychosocial disorders. The following instruments were applied: mini-mental state examination (cognitive impairment), Katz scale (index of independence), Beck depression inventory, geriatric depression scale (depression), Beck anxiety inventory (anxiety), and Lipp's stress symptom inventory for adults (stress). The quantity of medication used was also investigated. A descriptive analysis and Spearman's correlation test were performed. Results: Thirty-seven elderly individuals, mean age of 73.41 years, were included in the study. The mean DMFT index was 25.38. Mild to moderate depression was detected in 21.6%, anxiety in 45.9%, cognitive impairment in 78.4%, and lower polypharmacy rates in 54.1%. Age and oral health showed a moderate statistically significant positive correlation; age and cognitive impairment revealed a moderate negative correlation; and there was a strong and positive correlation between depression and the resistance stage of stress and between anxiety and the resistance stage of stress. Conclusions: There was correlation between oral health, anxiety, depression, stress, and medication in the investigated elderly sample.


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Anxiety , Oral Health , Depression , Drug Utilization
11.
Pesqui. bras. odontopediatria clín. integr ; 16(1): 185-193, jan.-dez. 2016. tab
Article in English | LILACS, BBO | ID: biblio-911345

ABSTRACT

Objective: To evaluate the association between oral health of babies aged 6-36 months and the Mother's Sense of Coherence (SOC). Material and Methods: A cross-sectional pilot study was conducted in the city of Diamantina -MG with a convenience sample of 32 mothers and their babies, attended at the Dental Clinic for Babies at the Federal University of the Vales do Jequitinhonha and Mucuri. The survey included the filling of dental records of babies, a questionnaire given to the mothers about sociodemographic and oral hygiene of their babies, and self-administered SOC-13. Babies were submitted to a clinical intra-oral examination for the detection of dental caries and initial lesions according to World Health Organization (WHO) criteria. Data were analyzed by the t test and Pearson's correlation (p<0.05). The size effect calculation proposed by Cohen was used to test the clinical significance of results. Results: The prevalence of dental caries was 40.0%. Maternal SOC had a variation between 35 and 59, with mean score of 47.7 (SD = 6.09). The monthly family income was more than two minimum wages for 51.6% of families. There was no statistically significant association between dental caries and maternal SOC (p = 0.646). Regarding monthly family income, there was a statistically significant association with maternal SOC (p = 0.005). Maternal SOC was also significantly associated with nocturnal oral hygiene of babies (p = 0.008). Conclusion: The mother's sense of coherence was not associated with dental caries and was associated with nocturnal oral hygiene of babies and with family monthly income.


Subject(s)
Humans , Infant , Child, Preschool , Dental Caries/prevention & control , Mothers , Oral Health , Sense of Coherence , Brazil , Cross-Sectional Studies/methods , Data Interpretation, Statistical , Surveys and Questionnaires
12.
Braz. dent. sci ; 19(2): 82-88, 2016. ilus
Article in English | LILACS | ID: lil-788627

ABSTRACT

In this study, the expression of extra cellular matrix proteins was immunohisto chemically studied and compared with the histological grading of squamous cell carcinomas of the lower lip and tongue. Material and Methods: The lower lip carcinomas (n =12) and the tongue carcinomas (n = 12) were histopathologically graded according to Bryne’smethod. The immunohisto chemical technique used specific antibodies for collagen IV and laminin. Histopathological and immunohisto chemical analysis were carried-out at the invasive tumor front. Results: Most of the lower lip carcinomas(91.7%) were classified with lower scores and all tongue carcinomas (100%) with high-grade malignant scores (p < 0.01). Collagen type IV expression was absent in the peri tumoral basement membrane in 50% of lower lip carcinomas and in66. 7% of tongue carcinomas (p = 0.09). Laminin expression was absent in the peritumoral basement membrane in 66.7% of lower lip carcinomas and in 58.3% of tongue carcinomas (p = 0.48). When these two glycoproteins were expressed, they showed alinear, thin and discontinuous pattern and a weak intensity of expression. Conclusion: The high gradem alignancy score of the tongue carcinomas was associated with the pattern of expression of the matrix proteins studied. This suggested that tonguesquamous cell carcinomas have more invasive potential and more aggressive biological behaviorthan the lower lip carcinomas...


Neste estudo, a expressão das proteínas da matriz extracelular foi estuda da imunoisto quimicamente e comparada com a classificação histológica dos carcinomas de células escamosas do lábio inferior e língua. Material e Métodos: Os carcinomas de lábio inferior (n = 12)e os carcinomas de língua (n = 12) foram graduados histopatologicamente de acordo com o método de Bryne. A técnica de imunoistoquímica utilizou anticorpos específicos para colágeno IV e laminina. Análises histopatológica e imunoistoquímica foram conduzidas na frente invasiva tumoral. Resultados: A maioria dos carcinomas de lábio inferior (91,7%) foi classificada em baixo grau e todos os carcinomas de língua (100%) em alto grau de malignidade (p < 0,01). A expressão de colágeno tipo IV estava ausente na membrana basal peri tumoral em 50% dos carcinomas de lábio inferior e em 66,7% dos carcinomas de língua (p = 0,09). A expressão de laminina estava ausente na membrana basal peri tumoral em 66,7%dos carcinomas do lábio inferior e em 58,3% dos carcinomas de língua (p = 0,48). Quando estas duas glicoproteínas foram expressas, mostraram-se comum padrão linear, fino e descontínuo e uma fraca intensidade de expressão. Conclusão: O alto grau de malignidade dos carcinomas de língua associou-se com o padrão de expressão das proteínas de matriz estudadas. Isso sugere que carcinomas de células escamosas de língua têm comportamento biológico mais agressivo e potencial mais invasivo do que os carcinomas de lábio inferior...


Subject(s)
Humans , Carcinoma , Collagen Type IV
13.
Sci. med ; 25(2): ID20918, abr.-jun. 2015.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-832086

ABSTRACT

Objetivos: Realizar um levantamento epidemiológico da saúde bucal e fatores psicossociais associados abrangendo indivíduos com idade igual ou superior a 60 anos. Métodos: Trata-se de um estudo transversal, com a população-alvo constituída de idosos. Foi selecionada uma amostra representativa do município de Diamantina, estado de Minas Gerais, composta por pessoas com mais de 60 anos, cadastradas nos postos da Estratégia Saúde da Família da zona rural e urbana do município. Os dados foram coletados em domicílio, por meio de exames bucais realizados por um único examinador, treinado e calibrado, e de questionários. Foi investigado o índice CPOD (média de dentes cariados, perdidos e obturados em um grupo de indivíduos), assim como dados sociodemográficos. Também foram obtidos dados sobre qualidade de vida relacionada à saúde bucal, locus de controle de saúde, consumo de álcool e drogas na senescência. Os dados obtidos foram submetidos à análise descritiva e ao teste de correlação de Spearman. O nível de significância adotado foi de ≤5%. Resultados: Foram entrevistados 37 idosos com idade média de 73,41±7,25 anos. O índice CPOD encontrado foi de 25,38±5,18. Houve correlação estatisticamente significante entre maior pontuação no domínio limitação funcional e maior idade, maior locus externo e maior locus ao acaso, aumento na limitação funcional e diminuição da renda, maior pontuação no domínio limitação funcional e maior locus interno, maior índice CPOD e menor pontuação no domínio incapacidade social. Conclusões: Pelo presente estudo concluiu-se que a qualidade de vida, locus de controle de saúde e índice CPOD são fatores diretamente correlacionados em idosos. Enfatiza-se a importância da atuação de profissionais de saúde e, mais especificamente, de saúde bucal, na promoção de um envelhecimento saudável.


Aims: To conduct an epidemiological survey on oral health and psychosocial factors in individuals aged 60 years or older. Methods: This is a cross-sectional study with elderly individuals as the target population. A representative sample of Diamantina, a town in Minas Gerais State, southeastern Brazil, was used. The sample consisted of individuals aged over 60 years registered at Family Health Strategy units in the rural and urban areas of Diamantina. Data were collected at home by means of oral examinations performed by a single trained and calibrated examiner, and through questionnaires. The decayed, missing and filled teeth (DMFT) index and sociodemographic data were investigated. Data on oral health-related quality of life, health locus of control, and use of alcohol and drugs in old age were also obtained. Results: Thirty-seven elderly individuals with a mean age of 73.41±7.25 years were interviewed. The average DMFT index was equal to 25.38±5.18. There was a statistically significant correlation between functional limitations and age, external locus and random locus, functional limitation and income, functional limitation and internal locus, and DMFT index and social disability. Conclusions: It can be concluded that quality of life, health locus of control, and DMFT index are correlated factors in the elderly. Health professionals should act in seeking to promote healthy aging.

SELECTION OF CITATIONS
SEARCH DETAIL